RECELL® Spray-On Skin

The RECELL System is approved for the treatment of burn wounds and full-thickness skin defects, and for re-pigmentation of stable depigmented vitiligo lesions. RECELL harnesses the regenerative properties of a patient’s own skin to create Spray-On Skin™ cells, delivering a transformative solution at the point-of-care. This breakthrough technology serves as the catalyst for a new treatment paradigm enabling improved clinical outcomes.

RECELL® Spray-On Skin Australian distributor

Benefits Beyond Closure™

Expedite the healing process with early treatment at a cellular level

RECELL uses a small piece of the patient’s skin to create a multi-phenotype suspension of Spray-On Skin™ Cells.[1]   The application of different cell types stimulates healing and re-pigmentation throughout the wound bed.[2,3]

The power of multi-phenotype Spray-On Skin Cells.

Autologous therapy at point-of-care allows for delivery of the patient’s own living cells:

KERATINOCYTES

regenerate the epidermis[4,5]

Dermal FIBROBLAST

deposit new extracellular matrix proteins[4]

MELANOCYTES

produce melanin to allow restoration of natural pigmentation[5]

1. Wood FM, Giles N, Stevenson A, Rea S, Fear M. Characterisation of the cell suspension harvested from the dermal epidermal junction using a ReCell® kit. Burns. Published online November 12, 2011. doi:10.1016/ j.Burns.2011.03.001.

2. Navarro FA, Stoner ML, Lee HB, et al. Melanocyte repopulation in full-thickness wounds using a cell spray apparatus. J Burn Care Rehabil 2001;22:41–6.
3. Navarro FA, Stoner ML, Park CS, et al. Sprayed keratinocyte suspensions accelerate epidermal coverage in a porcine microwound model. J Burn Care Rehabil 2000;21:513–8.

4. Freedberg I, Tomic-Canic M, Komine M, et al. Keratins and the Keratinocyte Activation Cycle J Invest Dermatol 116:633-640, 2001.
5. Hirobe T. Keratinocytes regulate the function of melanocytes. Dermatol Sin. 2014;32(4):200-204.

4. Freedberg I, Tomic-Canic M, Komine M, et al. Keratins and the Keratinocyte Activation Cycle J Invest Dermatol 116:633-640, 2001.

5. Hirobe T. Keratinocytes regulate the function of melanocytes. Dermatol Sin. 2014;32(4):200-204.

Caring for your patients means more than closing the wound.

With RECELL, you can expedite the healing process with early point-of-care treatment of burn wounds and full-thickness skin defects providing the best possible outcomes for patients. Designed for donor sparing, significantly less donor skin is required with similar healing outcomes versus conventional autografting.

Image

AVERAGE LESS DONOR SKIN FOR DPT BURNS[6]

AVERAGE LESS DONOR SKIN FOR FULL-THICKNESS BURNS WHEN USED IN COMBINATION WITH AUTOGRAFT[7]

AVERAGE LESS DONOR SKIN FOR FULL-THICKNESS SKIN DEFECTS WHEN USED IN COMBINATION WITH AUTOGRAFT[8]

STEP-BY-STEP Immediate Cellular Delivery

Cost-effective point-of-care regenerative therapy in a single procedure[8,9]

Obtain

Harvest skin sample[8]

1cm2 donor skin treats up to 80cm2

22 November 2024

Prepare

Isolate cells[8]

Non-cultured, patient-derived cells

22 November 2024

Deliver

RECELL treatment[8]

Promotes epidermal regeneration

22 November 2024
RECELL offers up to 80x expansion
RECELL offers up to 80x expansion

6. Holmes JH, Molnar JA, Carter JE, et al. A comparative study of the RECELL® device and autologous split-thickness meshed skin graft in the treatment of acute burn injuries. J Burn Care Res.2018 Aug 17;39(5):694-702.

7. Holmes JH, Molnar JA, Shupp JW, et al. Demonstration of the safety and effectiveness of the RECELL® system combined with split-thickness meshed autografts for the reduction of donor skin to treat mixed-depth burn injuries. Burns.2019;45(4):772-782. Care Res. 2018;39(5):694-702.

8. Instructions for Use. RECELL® Autologous Cell Harvesting Device.

8. Instructions for Use. RECELL® Autologous Cell Harvesting Device.
9. Kowal S, Kruger E, Bilir P, et al. Cost effectiveness of the use of autologous cell harvesting device compared to standard of care for treatment of severe burns in the United States. Adv Ther.Published online May 7, 2019. doi: 10.1007/s12325-019-00961-2.

9. Kowal S, Kruger E, Bilir P, et al. Cost effectiveness of the use of autologous cell harvesting device compared to standard of care for treatment of severe burns in the United States. Adv Ther.Published online May 7, 2019. doi: 10.1007/s12325-019-00961-2.

9. Kowal S, Kruger E, Bilir P, et al. Cost effectiveness of the use of autologous cell harvesting device compared to standard of care for treatment of severe burns in the United States. Adv Ther.Published online May 7, 2019. doi: 10.1007/s12325-019-00961-2.
10. Foster K, Bilir P, Kruger E, et al. Cost-effectiveness of RECELL® Autologous Cell Harvesting Device (ACHD) versus STSG for treatment of severe burns in the United States. Presented at the American Burn Association 2018 Annual Meeting, April 2018.
11. Carter JE, Carson JS, Hickerson WL, et al. Length of Stay and Costs with Autologous Skin Cell Suspension Versus Split-Thickness Skin Grafts: Burn Care Data from US Centers [published online ahead of print, 2022 Sep 14]. Adv Ther.2022;10.1007/s12325-022-02306-y. doi :10.1007/s12325-022-02306-y.
12. Carson JS, Carter JE, Hickerson WL, et al. Analysis of real-world length of stay data and costs associated with use of autologous skin cell suspension for the treatment of small burns in U.S. centers [published online ahead of print, 2022 Dec 5]. Burns. 2022; S0305-4179(22)00299-6. doi: 10.1016/j. burns.2022.11.007.

Clinical benefits of RECELL can lead to cost savings.[9]

Reduced donor skin requirements can result in fewer surgical procedures for definitive closure, decreased length of stay, and reduced resource use, translating to potential cost savings.[9-12]

UP TO 50% REDUCTION IN DEFINITIVE CLOSURE
PROCEDURES[9]

UP TO 47% REDUCTION IN LENGTH OF STAY FOR BURNS <50% TBSA[9]

UP TO 39% TOTAL COST SAVINGS[9]

AUSTRALIA

Revolution Surgical Pty Ltd
4/22 Rowood Road, Prospect NSW 2148
ABN: 63 165 643 434

NEW ZEALAND

Revolution Surgical New Zealand Ltd
378 Neilson Street, Penrose Auckland 1061 New Zealand
NZBN: 145-925-924

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